Ranitidine : Indication, Dosage, Side-effects, Brand name

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In this blog, I will give you information regarding Ranitidine medicine.Ranitidine is sold under brand name of Aciloc is useful in acidity.Acidity or heartburn is common problem now a days due to our life style,our food habits,etc.
RANITIDINERANITIDINE

Ranitidine is discovered in England in 1976 and come into commercial use since 1981.As per W.H.O. it is most essential, effective & safest drug.

In september 2019, the carcinogen N-nitrosodimethylamine (NDMA) was discovered in ranitidine medicine from many manufacturers, resulting in recalls.In April 2020, it was withdrawn from the US market and suspended in the European union due to same concern.It will be available in future or not, it will be clear with time.

So,this is very important topic to learn.We learn here

It can be taken by mouth,by injection into a muscle, or into a vein.

INDICATION OF RANITIDINE

  1. Acidity or heartburn
  2. Gastro-oesophageal reflux
  3. Erosive oesophagitis
  4. Gastric and duodenal ulcer
  5. Prevention of Stress induced ulcer in critically ill patients
  6. Zollinger-Ellison syndrome (ZES)
  7. Prevention of acid-aspiration pneumonitis during surgery:
    Ranitidine can be administered preoperatively to reduce the risk of aspiration pneumonia.The drug increases gastric
    PH but generally has no effect on gastric volume.
    In a 2009, meta-analysis comparing the net benefit of proton pump inhibitors and ranitidine to reduce the risk of aspiration before anaesthesia, ranitidine was found to be more effective than PPI (proton pump inhibitor) in reducing the volume of gastric secretions.
    Ranitidine may have an anti-emetic effect when administered before operation.
  8. Also useful in urticaria or hivesIn this way, Ranitidine is useful for many conditions.It is very important point that how it works? After taking this medicine, ranitidine block histaminic H2 receptors in stomach and prevent histamine mediated gastric juice secretion.
    Gastric juice means gastric acid, when gastric juice secretion decreases automatically we feel better in acidity & helps us in above conditions. Go To List 

DOSAGE INDICATION OF RANITIDINE

In Adults it is approxly 150mg to 600mg daily in two divided doses or a single bedtime dose given.

It is not indicated in children below 8 years.

Above 8 years of age it is given 2-4mg/kg/day.

Onset of effect starts within 1 hour & effect last for 12 hours. Go To List

ADVERSE EFFECTS

Each & every molecule which have effect, it has also side-effect.We can not deny adverse effect or side-effect.But it is not happen to everybody, it only occurs to someone who have sensitivity to particular molecule.

It is patient’s responsibility that they should bring sensitivity report with them if any, while consulting doctor.

If adverse effect occur, that may like as below.

  • Nausea,diarrhoea,constipation
  • Dizziness,headache
  • Allergy – itching,rashes
  • Insomnia,depression,hallucination, confusion
  • Jaundice,hepatitis
  • Thrombocytopenia,leucopenia

One important point I want to discuss here that now a days many people taking medicines everyday but not changing their life style to avoid problem.

We must change our life style,take less tea,take less fried and spicy to avoid acidity like problem repeatedly.

If we take this kind of medicine in routine than vitamin B12 deficiency may occur. Gastric acid is also need for kill harmful bacteria. If we take this kind of medicine daily than we may suffer from disease like typhoid or diarrhoea. Go To List

BRAND NAMES & STRENTH

  • Aciloc made by cadila
  • Histac made by ranbaxy
  • Ranitin made by torrent

It is available in both oral tablet,syrup and in injection form in below strenth.

Hope this article is helpful to you.Kindly comment or mail me for any kind of query.To watch video click below link.