Piroxicam medicine : Indication, Dosage, Side-effect

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In this blog, we learn about piroxicam medicine which is sold under brand names like proxy, doloforce, feldene, etc.

piroxicam medicine
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Piroxicam is NSAID means non steroidal anti-inflammatory drug, which use to treat painful inflammatory conditions like arthritis.

It was patented in 1968 by Pfizer company and approved for medical use since 1979.It became generic medixine in 1992 and is marketed worldwide under many brand names.

We learn this topic in below format

INDICATION OF PIROXICAM

This medicine is useful in below mention conditions

  • Ankylosing spondylitis
  • Rheumatoid arthritis
  • Osteoarthritis
  • Pain after operation
  • Acute gout
  • Menstrual pain – dysmenorrhea
  • Acute Musculoskeletal disorder

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Contraindication 

It means piroxicam medicine should be avoid to below conditions 

  • Recurrent peptic ulcer
  • Active peptic ulcer
  • Allergy due to painkiller
  • Hypersensitivity to this molecule
  • Bronchial asthma

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DOSAGE OF PIROXICAM

Adult
20mg once daily. Dosage can be up or down as per need by doctor.

Children
Less than 15kg weight – 5mg once
15 to 25 kg weight – 10mg once
26 to 45 kg weight – 15mg once

Effect starts within 3-4 hrs after taking piroxicam medicine & effect last for upto 2 days or more.

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SIDE-EFFECT OF PIROXICAM

Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.

If adverse effect occurs, that may be one of below

  • Nausea, vomiting
  • Rashes over body
  • Epigastric distress
  • Acidity
  • Oedema
  • Tinnitus

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SPECIAL PRECAUTIONS

  • Use cautiously in liver & kidney disease
  • Haemorrhagic disorder
  • Cardiovascular disease
  • Not recommended below 6 years of age

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MECHANISM OF ACTION

How it controls the pain?

When we got injury, there is increase secretion of prostaglandin by our body

It causes nerve stimulation & so, we feel pain

After taking Piroxicam, it blocks the synthesis of prostaglandin 

So, brain not recieved the message of pain temporarily

This way piroxicam controls pain. With time injured part heal & patient will feel completely okay.

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