In this blog, we learn about piroxicam medicine which is sold under brand names like proxy, doloforce, feldene, etc.
Piroxicam is NSAID means non steroidal anti-inflammatory drug, which use to treat painful inflammatory conditions like arthritis.
It was patented in 1968 by Pfizer company and approved for medical use since 1979.It became generic medixine in 1992 and is marketed worldwide under many brand names.
We learn this topic in below format
INDICATION OF PIROXICAM
This medicine is useful in below mention conditions
- Ankylosing spondylitis
- Rheumatoid arthritis
- Pain after operation
- Acute gout
- Menstrual pain – dysmenorrhea
- Acute Musculoskeletal disorder
It means piroxicam medicine should be avoid to below conditions
- Recurrent peptic ulcer
- Active peptic ulcer
- Allergy due to painkiller
- Hypersensitivity to this molecule
- Bronchial asthma
DOSAGE OF PIROXICAM
20mg once daily. Dosage can be up or down as per need by doctor.
Effect starts within 3-4 hrs after taking piroxicam medicine & effect last for upto 2 days or more.
SIDE-EFFECT OF PIROXICAM
Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.
If adverse effect occurs, that may be one of below
- Use cautiously in liver & kidney disease
- Haemorrhagic disorder
- Cardiovascular disease
- Not recommended below 6 years of age
MECHANISM OF ACTION
How it controls the pain?
When we got injury, there is increase secretion of prostaglandin by our body
It causes nerve stimulation & so, we feel pain
After taking Piroxicam, it blocks the synthesis of prostaglandin
So, brain not recieved the message of pain temporarily
This way piroxicam controls pain. With time injured part heal & patient will feel completely okay.
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