Montelukast medicine : Indication, Dosage, Adverse effect

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In this blog, we learn about montelukast medicine. It is very common medicine which use for allergy, asthma, etc. Generally, Montelukast is available in market with combination of antihistaminic like levocetirizine.

montelukast medicine
montelukast structure

Montelukast was approved for medical use in the U.S.A. in 1998. It is available as a generic medication. In 2018, it was the 15th most commonly prescribed medication in the U.S.A.

We learn this medicine in below format

INDICATION

montelukast in asthma
asthma
  • Asthma
  • Aspirin sensitive asthmatics
  • Exercise induce bronchospasm
  • Allergic rhinitis in which there is running nose with nasal congestion
  • Urticaria – skin rashes due to allergy

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MECHANISM OF ACTION

  • It reduces the eosinophil levels and causes bronchodilation.
  • It reduces the bronchial hyperresponsiveness
  • Montelukast improves the lung function & reduce bronchial inflammation.

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DOSAGE

Adult
10mg tablet once in a day in evening

Child 
6 to 14 years  – 5mg tablet once in a day in evening
2.5 years & above – 4mg tablet or liquid once in a day in evening

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CONTRAINDICATIONS

This medicine should be avoid in patient who have

  • Hypersensitivity to this molecule
  • Patient having acute asthma attacks

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ADVERSE EFFECTS

Each & every molecule which have effect, it has also side-effect. We can not deny adverse effect or side-effect. But it is not happen to everybody, it only occurs to someone who have sensitivity to particular molecule.

If patient have known sensitivity to any medicine, than they should show it to your consulting doctor.

If adverse effect occurs than it may be one of below

  • Nausea, vomiting, diarrhoea
  • Abdominal pain
  • Headache
  • Rashes over body
  • Dizziness
  • Sinusitis

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SPECIAL PRECAUTIONS

  • It should not be abruptly substituted for inhaled or oral corticosteroids.
  • Use cautiously in pregnant women, lactating women.
  • Avoid Montelukast in patient having kidney or liver problem.
  • It should not be give to children below 2 years of age.

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BRAND NAMES & STRENTH

It is availbale in market under brand names of Singulair, montair, etc.

Strenth
Montelukast available as a single content & combination with levocetirizine
10mg tablet
5mg tablet
4mg tablet

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