In this blog, we learn about Ivermectin medicine which is available in market with brand names like vermact, stromectol, etc.
This medicine is helps to treat many types of parasite infestations like whipworm, roundworm, thread worm, scabies, head lice, lymphatic filariasis, etc.
It can be taken by mouth or applied to the skin for external infestations.
We learn this topic in below format
INDICATION OF IVERMECTIN
Skin disease caused by mite. In which there is severe itching at night
It is parasitic disease caused by infection of roundworms.
In this disease, limb or other part of body becomes grossly enlarged due to obstruction of the lymphatic vessel.
- Round worm infestation
- Whip worm infestation
- Thread worm infestation
- Pinworm infestation
- River blindness
- Covid 19
Some studies suggest that this medicine can reduce the viral replication. This way it may be helpful in covid 19. However, there is controversy behind it. But, many countries using ivermectin in covid19.
This medicine should not to patient who have
DOSAGE OF IVERMECTIN
It is given single dose therapy
Approx dose – 0.2mg /kg single dose
12mg tablet generally given
Once you take ivermectin medicine, effect of this drug will last for about 12 days in your body.
SIDE-EFFECT OF IVERMECTIN
Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.
If adverse effect occurs, that may be one of below
It remains unclear that it is sage during pregnancy or not. So, better to avoid ivermectin during pregnancy. Ivermectin is secreted in very less amount in breast milk.
MECHANISM OF ACTION
Ivermectin act by interfering with nerve and muscle function of parasite and insects.
This drug bind with glutamate gated chloride ion channels .
It leads to increase permeability of the cell membrane to chloride ion.
Finally, hyperpolarisation of nerve or muscle cell causes paralysis and death of parasite.
BRAND NAMES & STRENTH
It is available in market with brand names like vemact, stromectol, iverdis, imectin, etc.
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