Ethamsylate medicine : Indication, Dosage, Side-effect

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In this blog, we learn about Ethamsylate medicine. This is very important medicine for stoppage of blood in many conditions like nasal bleeding, blood in vomit, blood in cough, etc. Which is available in market under brand names like ethasyl, alstat, etc.

ethamsylate medicine
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Ethamsylate (also known as etamsylate) is an antihemorrhagic agent which is believed to work by increasing resistance in the endothelium of capillaries and promoting platelet adhesion & helps in stoppage of bleeding.

Ethamsylate is available in both tablet and injection form.

We learn this medicine in below format

INDICATION OF ETHAMSYLATE

Ethamsylate medicine is useful in below conditions

  • Haematemesis – blood in vomiting
  • Haemoptysis – blood in cough
  • Haematuria – blood in urine
  • Epistaxis – blood from nose
  • DUB – dysfunction uterine bleeding
  • Primary menorrhagia
  • Postabortion or postpartum haemorrhage
  • Pre or post surgical haemorrhagic disorder
  • Premature infant
  • Prophylactically, all pre or post surgical procedure

CONTRAINDICATION 

  • Hypersensitivity to this molecule
  • Thrombocytic purpura
  • Haemophilia
  • Pregnancy and lactation

DOSAGE OF ETHAMSYLATE

Adult
500mg three time in a day

Children
250mg three time in a day

Peri-operative bleeding
250-500mg injection i/v or i/m at every 4-6 hours till bleeding stop

Effect of medicine last for more than 3 days after stopping the treatment

SIDE EFFECT

Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.

If adverse effect occurs, that may be one of below

  • Nausea, vomiting
  • Headache
  • Rashes over body
  • Transient hypotension in i/v-i/m injection

SPECIAL PRECAUTION 

  • Use cautiously in acute porphyria
  • Use cautiously in vaginal surgery

MECHANISM OF ACTION

It stops small vessels haemorrhage by stabilizing the capillary wall.

Ethamsylate increasing resistance in the endothelium of capillaries and promoting platelet adhesion & helps in stoppage of bleeding.

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