Diclofenac medicine : Indication, Dosage, Side-effect

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In this blog, we learn about Diclofenac medicine which is available under the brand name of dynapar, cataflam, dyloject, cambia, zipsor, etc. Which is available in oral tablet, injection form & in cream base to apply on skin.

diclofenac medicine
diclofenac structure

Diclofenac is a NSAID means non steroidal anti-inflammatory drug. This medicine is commonly used to pain, inflammation, sprain, etc.

Diclofenac was patented in 1965 by Ciba-Geigy. It came into medical use in U.S.A. since 1988. It is available as generic medicine. 

We learn this medicine in below format

INDICATION OF DICLOFENAC

diclo in pain
body pain
  • Dicofenac is given for pain & inflammation, as mention below
  • Osteoarthritis
  • Rhumatoid arthritis
  • Ankylosing spondylitis
  • Acute painful shoulder
  • Musculoskeletal disease
  • Menstrual pain – dysmenorrhoea
  • Sprain, dislocation,
  • Tenosynovitis, tendinitis – inflammation of tendon
  • Pain after operation

CONTRAINDICATION OF DICLOFENAC

It means we should not give this medicine to the patient, who have below complains. 

  • Having hypersensitivity to this molecule or other NSAID
  • Allergic asthma after taking NSAID
  • Active peptic ulcer
  • Gastro-intestinal bleeding
  • Kidney &  liver  problem

SIDE EFFECT

Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.

If adverse effect occurs, that may be one of below

  • Nausea, vomiting, GI bleeding
  • Headache, dizziness, drowsiness
  • Rashes
  • Breathlessness/wheezing
  • Swollen feet/ankle

DOSAGE OF DICLOFENAC

Dosage is depends on patient’s weight, age & severity of complain. So, kindly follow advise of your consulting doctor for taking medicine.

Adult
100 to 150mg per day in divided doses if needed
50mg twice daily is maintaining dose
75mg in injection form once daily for 2 days or as per need

Children (1 to 12 years)
1-3mg/kg/day in divided doses

Effect of diclofenac starts within 1 hour & effect last for upto 12 hrs. In sustain release tablet effect last for upto 24 hours.

MODE OF ACTION

How it controls the pain?

When we got injury, there is increase secretion of prostaglandin by our body

It causes nerve stimulation & so, we feel pain

After taking diclofenac, it blocks the synthesis of prostaglandin 

So, brain not recieved the message of pain temporarily

This way diclofenac controls pain. With time injured part heal & patient will feel completely okay.

STRENGTH & BRAND NAMES

This medicine is available in tablet & injection form.

Brand names
Dynapar, voltaren, voltarol, cataflam, dyloject, cambia, zipsor, etc.

Strenth
50mg tablet
75mg per ml in injection form
25mg per ml in injection form

It is also available in combination with paracetamol
50mg aceclofenac + 325mg paracetamol

DICLOFENAC IN PREGNANCY

It is not recommended in the third trimester of pregnancy. It is likely safe during breast feeding.

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