Aceclofenac medicine : Indication, Dosage, Side-effect

In this blog, we learn about Aceclofenac medicine which is available under the brand name of zerodol, hifenac, clanza CR, acecgen, aflame, etc. 

Aceclofenac is a NSAID means non steroidal anti-inflammatory drug related to diclofenac. This medicine is commonly used to pain, inflammation in rheumatoid arthritis, Osteoarthritis, etc.

We learn this medicine in below format

• Indication
• Contraindication
• Dosage
• Side-effect
• Special precaution
• Brand names & strength

INDICATION OF ACECLOFENAC

• Pain & inflammation
• Osteoarthritis
• Rhumatoid arthritis
• Ankylosing spondylitis
• Injury or trauma
• Inflammation after operation
• Degenerative arthropathies

CONTRAINDICATION

It means we should not give this medicine to the patient, who have below complains. 

• Having hypersensitivity to this molecule or other NSAID
• Kidney, liver or other cardiac problem
• Old age having risk of side-effect

DOSAGE OF ACECLOFENAC

Adult
100mg tablet twice daily

Effect of aceclofenac starts within 1 hour & effect last for upto 12 hrs. In sustain release tablet effect last for upto 24 hours.

SIDE EFFECT OF ACECLOFENAC

Each & every molecule which have effect also have side-effect. But, it not occurs to everyone. It occurs to only who have sensitivity to particular molecule.

If adverse effect occurs, that may be one of below

• Nausea, vomiting, GI bleeding
• Headache, dizziness
• Rashes
• Breathlessness/wheezing

MODE OF ACTION

How it controls the pain?

When we got injury, there is increase secretion of prostaglandin by our body

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It causes nerve stimulation & so, we feel pain

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After taking this medicine, it blocks the synthesis of prostaglandin 

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So, brain not recieved the message of pain temporarily

This way aceclofenac controls pain. With time injured part heal & patient will feel completely okay.

STRENGTH & BRAND NAMES

This medicine is available in tablet form.

Brand names
Zerodol, acecgen, aflame, flemac, hifenac, clanza CR, etc.

Strenth
100mg & 200mg tablet

It is also available in combination with paracetamol
100mg aceclofenac + 325mg paracetamol

ACECLOFENAC IN PREGNANCY & LACTATION

Breast-feeding mothers should not take this medicine. It should be avoided near term in a pregnant woman because of the risk of having a premature closure of ductus arteriosus leading to fetal hydrops in the neonate.

It should be avoid in children

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